Evaluation of Invasive Capabilities of Bacterial Isolates from Infected Ears of Children

Student: PETER TOBI BABALOLA (Project, 2025)
Department of Microbiology
University of Benin, Benin City, Edo State


Abstract

Ear infections (otitis media and otitis externa) are among the most common bacterial infections affecting children worldwide, often leading to hearing impairment if not promptly managed. This study evaluated the invasive capabilities of bacterial isolates obtained from infected ears of children attending selected hospitals in [Your Study Area]. Ear swab samples were collected and analyzed using standard microbiological techniques, including culture, biochemical identification, and antibiotic susceptibility testing. Selected isolates were subjected to invasion assays using human epithelial cell lines to assess their invasive potentials. Results revealed that Staphylococcus aureus, Pseudomonas aeruginosa, Proteus mirabilis, and Klebsiella pneumoniae were the predominant pathogens isolated. Among these, Pseudomonas aeruginosa and Staphylococcus aureus exhibited the highest invasive capabilities. The study highlights the pathogenic potential of bacterial isolates from pediatric ear infections and emphasizes the need for rational antibiotic use, proper hygiene, and continuous surveillance to prevent complications associated with invasive ear infections.

Keywords
evaluation invasive capabilities bacterial isolates infected children