Antibiotic Susceptibility Profile of Escherichia Coli and Other Related Bacteria Associated With Urine of Pregnant Women in Benue State University Teaching Hospital, Makurd

Urinary tract infection is a major public health problem in terms of morbidity and financial cost and represents one of the most common diseases encountered in medical practice today with an estimated 150 million UTis per annum worldwide. It remains a commonly diagnosed infection both in community as wells as in hospitalized pregnant mothers and Escherichia coli was found to be the most common pathogen of UTI both in community and hospital acquired infections. The main objective determines antibiotic susceptibility profile of bacteria associated with urine of pregnant women. The study was a Cross-sectional descriptive study where systematic sampling was used to recruit the respondents that meet the inclusion criteria fifty (100) sample are used for pregnant women from trimester 1, 2 and 3 respectively participating in the study. Demographic and risk factors details were obtained through a structured Check List interviews. Data was analyzed using Microsoft Excel and presented in tables and graphs presentation. Coding and verification of the data was done before data analyzed. Analysis was done using SPSS version 15, Chi-square test (2x2) or Fishers Exact Test was applicable at P-value derivation for socio-demographic and risk factors to identify variables associated with UTIs. Antimicrobial susceptibility pattern rate of gram negative bacteria ranged from 27% to 92% to be accurate Susceptibility was as Cefriaxozone 74 (92%), Ciprofloxacin 56 (70%), Gentamycin 56 (70%), co-Trimoxazole 55 (69%, Ampicillin 50 (63%), Chloraphenical 40 (50%, Streptomycin 32 (43%) and Tetracycline 22 (27%) respectively.