Identification of Prevalence of Malaria and Dengue Virus Co-Infection Among Adults Reporting With Febrile Illness at Murtala Muhammad Specialist Hospital, Kano

Student: RIDWAN DOGO Shuaib (Project, 2025)
Department of Biochemistry
Bayero University, Kano, Kano State


Abstract

Mosquito-borne diseases, particularly malaria and dengue fever, pose significant public health concerns in tropical and subtropical regions. While both diseases share similar clinical symptoms, their concurrent infection (co-infection) remains underreported, often leading to misdiagnosis and improper treatment. This study aimed to identify the prevalence of malaria and dengue virus co-infection among adults presenting with febrile illness at Bayero University Kano (BUK) Clinics. A total of 75 febrile patients were screened for malaria and dengue infection using Rapid Diagnostic Tests (RDTs), with malaria-positive cases confirmed via Polymerase Chain Reaction (PCR) by amplification of cytochrome oxidase I (COX-I). The results indicated a malaria prevalence of 4% (3 out of 75), while no cases of dengue infection or malaria-dengue co-infection were detected. The absence of dengue-positive cases suggests a lower prevalence in the study population or seasonal variations in transmission. Despite existing reports of malaria-dengue co-infections in Nigeria, this study highlights the need for continuous surveillance, improved diagnostic accuracy, and awareness regarding dengue fever in Northern Nigeria. Further research involving larger sample sizes and year-round surveillance is recommended to better understand the epidemiology of these infections and to enhance public health interventions.

Keywords
Mosquito borne diseases mosquito vector Plasmodium DENV malaria dengue febrile illness Co-infection