The Effect of Ginger on Microorganisms in the Gastrointestinal Tract (git) of Albino Rats and Its Impact on Haematological Parameters

This study evaluated the effects of Ginger (Zingiber officinale Roscoe) on weight gain, gastrointestinal microbiota, and health parameters in albino rats. Twelve rats were acclimatized for two weeks before being divided into five groups: a control and four experimental groups receiving Ginger extract at doses of 250 ml, 500 ml, 750 ml, and 1000 ml over four weeks. Weight gain results demonstrated a dose-dependent response, with the lowest dose (250 ml) yielding the most significant weight increase, whereas higher doses resulted in more moderate gains. Microbiological analyses indicated that Ginger administration led to a substantial reduction in total heterotrophic bacterial counts across all treated groups compared to the control, with the lowest dose achieving the most pronounced decrease. The presence of harmful bacteria, such as Enterococcus faecalis and Staphylococcus aureus , was notably reduced, while beneficial gut flora like Lactobacillus plantarum became more prevalent in treated groups. Biochemical tests revealed shifts in microbial composition, with treated groups showing a reduction in pathogenic bacterial species and an increase in microbial diversity. haematological tests indicated dose-dependent variations in white blood cell counts, hemoglobin levels, and other blood parameters. Higher doses generally led to increased immune responses, as evidenced by elevated white blood cell and platelet counts, while some doses affected hemoglobin levels and other parameters differently over the study period. Overall, Ginger significantly influenced weight gain, microbial balance, and haematological parameters, highlighting its potential to enhance gastrointestinal health, support growth, and modulate immune function. These findings provide a basis for further investigation into Ginger’s therapeutic applications.