Effect of Immunebooster on Gastric Inflammatory Markers in Lead Exposed Male Wistar Rat
Student: Oluwaseun Ebenezer Komolafe (Project, 2025)
Department of Physiology
Ekiti State University, Ado-Ekiti, Ekiti State
Abstract
Lead exposure is known to induce oxidative stress and gastric inflammation, leading to significant tissue damage. This study investigates the effect of an immune booster on gastric inflammatory markers in lead-exposed male Wistar rats. Twenty-four rats were divided into control, lead-exposed, immune booster-treated, and lead + immune booster groups. Lead acetate was administered to induce toxicity, while the immune booster was given to evaluate its protective potential. Biochemical analysis of gastric tissues revealed that lead exposure significantly increased inflammatory markers, whereas treatment with the immune booster markedly reduced these levels and improved histological integrity. The findings suggest that the immune booster possesses anti-inflammatory and protective effects against lead-induced gastric injury.
Keywords
For the full publication, please contact the author directly at: komolafeoluwaseun23@gmail.com
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- UMA UKPAI SCHOOL OF THEOLOGY, UYO, AKWA IBOM STATE (AFFL TO UNIVERSITY OF UYO) 1
- Umaru Ali Shinkafi Polytechnic, Sokoto, Sokoto State 24
- Umaru Musa Yaradua University, Katsina, Katsina State 28
- Umca, Ilorin (Affiliated To University of Ibadan), Kwara State 1
- University of Abuja, Abuja, Fct 116
- University of Africa, Toru-Orua, Bayelsa State 4
- University of Benin, Benin City, Edo State 362
- University of Calabar Teaching Hospital School of Health Information Mgt. 1
- University of Calabar, Calabar, Cross River State 240
- University of Ibadan, Ibadan, Oyo State 14