Acute Toxicity and Haematological Assessment of the Methanolic, Ethanolic Extract and Pulverized Sample of Cleome Rutidosperma Leaves on Wistar Rats

Student: Faith Alaba Ayemoba (Project, 2025)
Department of Biochemistry
University of Benin, Benin City, Edo State

Abstract

Cleome rutidosperma is a plant species with medicinal properties, including anti-inflammatory, widely relied upon in traditional practices. For this reason, the present research was intended to assess and, thus, ensure the safety of this plant for conventional medicinal purposes using a toxicity test study. This research sought to access the acute toxicity and haematological assessment of the methanolic, ethanolic extract and pulverized samples of Cleome rutidosperma leaves in wistar albino rats. Acute toxicity was carried out using the OECD method were the animals were grouped into 16 groups, were group one was the control group and administered normal feed and water while group 2 to 6 were administered 10mg/kg body weight of methanolic extract (MET).

Keywords
NO METAL KEYWORD
Filters
Institutions