Evaluation of the in-Vitro Antibacterial and Anti-Inflammatory Potentials of the Tender Water of Cocos Nucifera (l.)

Student: Oghenovo Frances Offideh (Project, 2025)
Department of Pharmacy
Delta State University, Abraka, Delta State

Abstract

The aim of this study was to evaluate the antibacterial and anti-inflammatory potentials of the tender water of Cocos nucifera (L.). Antibacterial potentials of tender coconut water were assessed utilizing the agar well diffusion method, and the anti-inflammatory test was carried out by the Human Red Blood Cell (HRBC) membrane stabilization method, and the supernatant solution estimated using a UV-Visible spectrophotometer at a wavelength of 560 nm. The highest antimicrobial activity was observed against Pseudomonas aeruginosa with the minimum inhibitory concentration (MIC) being 50% concentrate of tender coconut water. The anti-inflammatory results revealed a notable anti-inflammatory activity of 30% as measured by hypotonicity induced hemolysis of the HRBC membrane using the UV-visible spectrophotometer at a wavelength of 560 nm. Qualitative phytochemical analysis indicated that tender coconut water contained major bioactive compounds such as alkaloids, polyphenols (flavonoids), and terpenoids which indicate high potentials of Cocos nucifera (L.) as a resplendent material for future ethnopharmacological research.

Keywords
anti-inflammatory tender water potentials antibacterial cocos nucifera coconut method membrane
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