Upshot of Azadirachta Indica Extract Augmented With Vitamin C on the Replication and Pathogenic Profile of Newcastle Disease Virus in a Day-Old Broiler Chicks

Student: Goodness Ojichukwu Anakebe (Project, 2025)
Department of Microbiology
Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State

Abstract

Newcastle disease is a highly contagious and devastating viral disease of the poultry with worldwide distribution and resulting in large economic loss among the poultry farmers. The aim of this is to evaluate the role of vitamin C in improving antiviral activity of Azadirachta indica leaves extract in broiler chicks. A total of sixteen (16) day old broiler chicks were used in this study which was grouped into 4. Group 1 and 2 were protected with Azadirachta indica leaves extract and a mixture of the extract and vitamin C (Neemvic) before being challenged with the virus whereas group 3 received only the virus and group 4 served as the control. The protective effects of the extracts were determined by observing the changes in body weight, organ weights, pathological features and lesions in broiler chicks. The study showed that Azadirachta indica leaves extract and Neemvic significantly (p

Keywords
Azadirachta indica vitamin C Neemvic Newcastle disease virus broiler chicks antiviral activity poultry health weight gain disease prevention
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