Biochemical and Histochemical Analysis of the Hippocampus Following in Utero Exposure to Enalapril in Pregnant Wistar Rats
Student: Comfort Moyinoluwa Isijola (Project, 2025)
Department of Anatomy
Ekiti State University, Ado-Ekiti, Ekiti State
Abstract
ABSTRACT Hypertension is the most common medical problem encountered during pregnancy, complicating 2-3% of pregnancies. Hypertensive disorders during pregnancy are classified into 4 categories; 1) chronic hypertension, 2) preeclampsia-eclampsia, 3) preeclampsia superimposed on chronic hypertension, and 4) gestational hypertension (transient hypertension of pregnancy or chronic hypertension identified in the latter half of pregnancy).Enalapril is an angiotensin-converting enzyme (ACE) inhibitor primarily used to treat hypertension and heart-related conditions, but its impact on the brain, including the hippocampus, can be complex and multifaceted. This study aimed to look at the effect of enalapril on the hippocampus of the pregnant rat pups.
Keywords
For the full publication, please contact the author directly at: comfortisijola@gmail.com
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Institutions
- Covenant Polytechnic, Aba, Abia State 1
- Covenant University, Canaan Land, Ota, Ogun State 4
- Crawford University of Apostolic Faith Mission Faith City, Igbesa, Ogun State 2
- Crescent University, Abeokuta, Ogun State 1
- Cross Rivers University of Technology, Calabar, Cross Rivers State 147
- Delta State Polytechnic, Ogwashi-Uku, Delta State 16
- Delta State Polytechnic, Otefe, Delta State 13
- Delta State University, Abraka, Delta State 145
- Ebonyi State University, Abakaliki, Ebonyi State 18
- Edo University, Iyamho, Edo State 11