Antimicrobial Effect of Garlic Extract on Candida Albicans Isolated from the Labia Majoras
Student: Oluwakemisola Busayo Ogundipe (Project, 2025)
Department of Microbiology
Lens Polytechnic, offa, Kwara State.
Abstract
This study investigates the antimicrobial effect of garlic (Allium sativum) extract on Candida albicans strains isolated from the labia majora of female patients presenting with candidiasis symptoms. Candida albicans is a common fungal pathogen associated with vulvovaginal candidiasis, which is often recurrent and resistant to conventional antifungal agents. Garlic, known for its bioactive compound allicin, exhibits promising antimicrobial properties. Clinical isolates of C. albicans were subjected to ethanolic and aqueous garlic extracts using agar well diffusion and minimum inhibitory concentration (MIC) assays. Results demonstrated a significant zone of inhibition with the ethanolic extract compared to the aqueous extract, with activity comparable to standard antifungal agents like fluconazole. This study supports the potential of garlic extract as an alternative or complementary antifungal treatment, especially in the era of increasing drug resistance.
Keywords
For the full publication, please contact the author directly at: ogundipeoluwakemisola@gmail.com
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Institutions
- Hassan Usman Katsina Polytechnic, Katsina, Katsina State 5
- Heritage Polytechnic, Ikot Udota, Akwa Ibom State 46
- Hussaini Adamu Federal Polytechnic, Kazaure, Jigawa State 8
- Ibrahim Badamasi Babangida University, Lapai, Niger State 24
- Igbinedion University, Okada, Benin City, Edo State 2
- Ignatius Ajuru University of Education, Port Harcourt, Rivers State 8
- Imo State Polytechnic, Umuagwo, Owerri, Imo State 3
- Imo State University, Owerri, Imo State 46
- Institute of Management and Technology, Enugu, Enugu State 11
- Isa Mustapha Agwai I Polytechnic, Lafia, Nasarawa State 2