Cardiological Investigation on the Heart of Pregnant Female Wistar Rats: the Histological and Biochemical Perspective
Student: Uchenna Tony Ukachukwu (Project, 2025)
Department of Anatomy
Ebonyi State University, Abakaliki, Ebonyi State
Abstract
This study delves into the cardiological changes occurring during pregnancy, with afocus on histological and biochemical perspectives. Pregnancy induces significantcardiovascular adaptations to support increased metabolic demands and ensure fetaldevelopment. We investigate these adaptations through a dual approach: histologicalanalysis of heart tissues and biochemical profiling of cardiac biomarkers.Histological studies reveal structural modifications in cardiac tissue, includingchanges in myocardial architecture, cellular hypertrophy, and angiogenesis.Concurrently, biochemical assays highlight alterations in key cardiac biomarkerssuch as natriuretic peptides, troponins, and oxidative stress markers. Our findingsprovide a comprehensive understanding of the cardiovascular system's dynamicresponse to pregnancy, offering insights into potential implications for maternal andfetal health. This research underscores the importance of monitoring cardiacfunction in pregnant women, paving the way for improved clinical management andoutcomes
Keywords
For the full publication, please contact the author directly at: ukachukwutony44@gmail.com
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Institutions
- UMA UKPAI SCHOOL OF THEOLOGY, UYO, AKWA IBOM STATE (AFFL TO UNIVERSITY OF UYO) 1
- Umaru Ali Shinkafi Polytechnic, Sokoto, Sokoto State 24
- Umaru Musa Yaradua University, Katsina, Katsina State 28
- Umca, Ilorin (Affiliated To University of Ibadan), Kwara State 1
- University of Abuja, Abuja, Fct 116
- University of Africa, Toru-Orua, Bayelsa State 4
- University of Benin, Benin City, Edo State 362
- University of Calabar Teaching Hospital School of Health Information Mgt. 1
- University of Calabar, Calabar, Cross River State 240
- University of Ibadan, Ibadan, Oyo State 14