The Effect of Chronic Sleep Deprivation on the Antioxidant Markers of Hearts of Rats Induced With Peptic Ulcer
Student: Jeffery Iretomiwa Ogungbuaro (Project, 2025)
Department of Human Physiology
Ekiti State University, Ado-Ekiti, Ekiti State
Abstract
The Impact of Sleep Deprivation on Peptic Ulcer Development and Progression Sleep deprivation, a prevalent modern-day issue, has been linked to various health complications. This study investigates the relationship between sleep deprivation and the development and progression of peptic ulcers. Peptic ulcers are painful sores in the lining of the stomach or duodenum, often caused by a combination of factors, including Helicobacter pylori infection and excessive acid production. Research suggests that chronic sleep deprivation can disrupt the body’s stress response, leading to increased cortisol levels. Elevated cortisol levels can promote gastric acid secretion and impair mucosal barrier integrity, making individuals more susceptible to peptic ulcer development. Additionally, sleep deprivation may negatively impact the immune system, hindering the body’s ability to combat H. pylori infection. This study aims to explore the mechanisms underlying the association between sleep deprivation and peptic ulcer disease, providing valuable insights for prevention and treatment strategies
Keywords
For the full publication, please contact the author directly at: ivanjeffery1@gmail.com
Filters
Institutions
- Covenant Polytechnic, Aba, Abia State 1
- Covenant University, Canaan Land, Ota, Ogun State 4
- Crawford University of Apostolic Faith Mission Faith City, Igbesa, Ogun State 2
- Crescent University, Abeokuta, Ogun State 1
- Cross Rivers University of Technology, Calabar, Cross Rivers State 142
- Delta State Polytechnic, Ogwashi-Uku, Delta State 11
- Delta State Polytechnic, Otefe, Delta State 13
- Delta State University, Abraka, Delta State 139
- Ebonyi State University, Abakaliki, Ebonyi State 17
- Edo University, Iyamho, Edo State 10