Preparation, Analysis and Anti Microbial Activities of Schiff Base Derive from Salycylaldehyde and Sulfonamide and It’s Metal(ii) Complexes
Student: David Okoro (Project, 2025)
Department of Pure and Industrial Chemistry
Bayero University, Kano, Kano State
Abstract
A Schiff-base derived from sulfonamide and salicylaldehyde, and its metal complexes of Cu (II), Co (II) and Ni (II) were prepared and analysed based on their solubility, molar conductance and infrared analyses. The Schiff base in an ethanolic solution was refluxed with the ethanolic solution of the metal in 2:1 molar ratio. Physical and analytical data suggested that the Schiff base act as tetradentate ligand towards the metal ions via azomethine-N. All the complexes have low molar conductance value (3.13-9.9Ω-1cm2 mol-1), indicating that they are non-electrolyte. The prepared ligand and its respective metal complexes were screened for their antibacterial activity against Staphylococcus aureus and Escherichia coli, bacterial strains. The results of these studies revealed that the metal complexes showed significant antibacterial activity at high concentrations.
Keywords
For the full publication, please contact the author directly at: davidokoro244@gmail.com
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Institutions
- HASSAN USMAN KATSINA POLYTECHNIC (NCE), KATSINA, KATSINA STATE 4
- Hassan Usman Katsina Polytechnic, Katsina, Katsina State 5
- Heritage Polytechnic, Ikot Udota, Akwa Ibom State 46
- Hussaini Adamu Federal Polytechnic, Kazaure, Jigawa State 8
- Ibrahim Badamasi Babangida University, Lapai, Niger State 24
- Igbinedion University, Okada, Benin City, Edo State 2
- Ignatius Ajuru University of Education, Port Harcourt, Rivers State 8
- Imo State Polytechnic, Umuagwo, Owerri, Imo State 3
- Imo State University, Owerri, Imo State 45
- Institute of Management and Technology, Enugu, Enugu State 11