The Effect of Quercetin on Erythrosine and Tartrazine Induced Depression Like Behaviour in Male Mice a Behavioural Approach

Student: chukwudi jonas chineke (Project, 2025)
Department of Biochemistry
University of Port-Harcourt, Rivers State

Abstract

This study investigated the ameliorative effects of quercetin and erythrosine, induced depression like behavior on mice (a behavioral approach). Fifly mice were divided into five groups of 10 mice per group. Control was given distilled water, negative control was given erythrosine and tartrazine (50mg/kg) while 50mg/kg and 100 mg/kg of quercetin w e r e administered to the test group, 50 mg/kg of vitamin C (positive control) for 28 days. After administration, the animals were euthanized under ketamine anaesthesia and sacrificed using spinal cord dislocation the brains were excised and sectioned. The hippocampus was isolated and homogenized. Cntri (65), ET (75), que 50 (S0), que 100 (60), and Vit C (125). in the dark and light phase. The treated groups reduced significantly (p

Keywords
effect quercetin erythrosine tartrazine induced depression behaviour behavioural approach
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