Effects of Ginger-Based Diets and Turmeric-Based Diets on Gluthathione-S-Transrerase Activity in the Brain and Serum of D-Galactose Induced Aging Rats.
Student: Ajoke Kareemat Olasupo (Project, 2025)
Department of Biochemistry
Ekiti State University, Ado-Ekiti, Ekiti State
Abstract
The effect of Ginger (Zingiber officinale R) based-diets and Turmeric (Curcuma longa L)based-dietson glutathione-s-transferase activities in serum and brain of D-galactose induced aging rats. Group 1(control group),Group 2(D-galactose induced),Group 3(D-galactose induced+2% turmeric powder),Group 4(D-galactose induced + 4% turmeric powder), Group 5(D-galactose induced + 2% ginger powder), Group 6(D-galactose induced + 4% ginger powder), Group 7(D-galactose induced +vitamin E(150mg/kg)). At the end of the feeding experiment,the animals were euthanized in chloroform anaesthesia and sacrificed. Blood was collected via cardiac puncture and the brain samples were harvested. Group 1 was which is the control group, Group 2(untreated) GSH activities on the brain and serum was significantly decreased compared to the other group. Group 5(Ginger at 2%) shows that there was little effect if GSH activities on the brain and serum of D-galactose induced aging rats. This study suggests that ginger can improve antioxidant status in oxidative stress.
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- School of Health Information Mgt (Uch, Ibadan), Oyo State 5
- School of Health Information Mgt, Oau Teaching Hospital, Ile-Ife, Osun State 30
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- Sokoto State University, Sokoto, Sokoto State 43
- St. Albert The Great Major Seminary, Abeokuta. (affl. To University of Benin) 1
- Sule Lamido University, Kafin Hausa, Jigawa State 4
- Tai Solarin University of Education, Ijagun, Ogun State 19
- Tansian University, Oba, Anambra State 1
- Taraba State University, Jalingo, Taraba State 32
- Temple-Gate Polytechnic, Osisioma, Abia State 1