The Effect of Immune Booster on Lung Oxidative Markers in Lead Expose Male Wistar Rats
Student: Bamikole Victor Ilesanmi (Project, 2025)
Department of Physiology
Ekiti State University, Ado-Ekiti, Ekiti State
Abstract
The impact of lead cannot be overemphasized in today’s world and its hazardous effect on the human race. Its exposure is a significant environmental health challenge that calls for attention.
Lead is known to cause compulsive stress and structural damage to different organs in the body, especially the lungs. This research examines the effect of an immune booster on lung oxidative markers in male Wistar rats exposed to lead, and the parameters assessed include body weight, lung weight, lung relative weight, and oxidative stress markers such as malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), glutathione S-transferase (GST), and glutathione peroxidase (GPx). Also, lung histology was examined to observe structural changes induced by lead exposure and any protective effects of the immune booster intervention.
Keywords
For the full publication, please contact the author directly at: ilesanmibamikole20@gmail.com
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Institutions
- HASSAN USMAN KATSINA POLYTECHNIC (NCE), KATSINA, KATSINA STATE 4
- Hassan Usman Katsina Polytechnic, Katsina, Katsina State 5
- Heritage Polytechnic, Ikot Udota, Akwa Ibom State 46
- Hussaini Adamu Federal Polytechnic, Kazaure, Jigawa State 8
- Ibrahim Badamasi Babangida University, Lapai, Niger State 24
- Igbinedion University, Okada, Benin City, Edo State 2
- Ignatius Ajuru University of Education, Port Harcourt, Rivers State 8
- Imo State Polytechnic, Umuagwo, Owerri, Imo State 3
- Imo State University, Owerri, Imo State 45
- Institute of Management and Technology, Enugu, Enugu State 11