Effects of Aqueous Leaves Extract of Ocimum Gratissimum on Some Liver Function Parameters of Albino Rats
Student: Nmesomachi Success Mathias (Project, 2025)
Department of Biochemistry
Federal Polytechnic, Nekede, Imo State
Abstract
ABSTRACT
This study investigated the effects of the aqueous leaves extract of Ocimum gratissimum on the liver function parameters of albino rats. This research determined the impact of Ocimum gratissimum leaves extract on Alkaline Phosphatase (ALP), Aspartate Aminotransferase (AST) and Alanine Transaminase (ALT) levels in albino rats. Twenty albino rats were grouped into four groups, each receiving different concentrations of the aqueous leaves extract of Ocimum gratissimum except group 1 (which served as control). Group 1 received only feed and water. Group 2, 3 and 4 received 100, 200, 300 mg/kg body weight of aqueous leaves extract of Ocimum gratissimum respectively. The administration of the extract was done orally for fourteen days. The animals were sacrificed by cervical dislocation and the blood was collected by cardiac puncture after the termination of the treatment. The samples were kept for further analysis. The result showed a significantly (P
Keywords
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- Abdul-Gusau Polytechnic, Talata-Mafara, Zamfara State 3
- Abia State Polytechnic, Aba, Abia State 24
- Abia State University, Uturu, Abia State 71
- Abraham Adesanya Polytechnic, Ijebu-Igbo, Ogun State 3
- Abubakar Tafawa Balewa University, Bauchi, Bauchi State 16
- Abubakar Tatari Ali Polytechnic, Bauchi State. (affiliated To Atbu Bauchi) 1
- Achievers University, Owo, Ondo State 6
- Adamawa State University, Mubi, Adamawa State 8
- Adekunle Ajasin University, Akungba-Akoko, Ondo State 27
- Adeleke University, Ede, Osun State 1