Assessment of Sterility of Five Different Brands of Injectable Gentamicin
Student: AISHA HARUNA MUHAMMAD (Project, 2025)
Department of Pharmaceutical Technology
Kano State Polytechnic, Kano, Kano State
Abstract
Sterility testing is a critical component of pharmaceutical quality control, especially for injectable drugs like gentamicin that bypass natural immune barriers upon administration. Ensuring these antibiotics are free from microbial contamination is essential to avoid severe health risks in patients. Traditional sterility testing methods include membrane filtration and direct inoculation; however, each method has its limitations, particularly when dealing with antibiotics possessing inherent antimicrobial properties (Sutton, 2011). This study investigates the direct inoculation method's effectiveness in detecting microbial contaminants in injectable gentamicin.
Substandard and falsified medicines are an enormous threat to global health. Poor quality antibiotic preparations contribute to the development of antimicrobial resistance. In surgery, where the occurrence of healthcare-associated infections is high, healthcare teams need to rely on the quality of antibiotic prophylaxis to prevent infections. We assessed the quality of antibiotics used for surgical infection prophylaxis in Benin
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For the full publication, please contact the author directly at: aishaharunamuhammad9@yopmail.com
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- Mohammed Lawan College of Agriculture, Maiduguri, Borno State 12
- Moshood Abiola Polytechnic, Abeokuta, Ogun State 7
- Nasarawa State University, Keffi, Nasarawa State 8
- Niger Delta University, Wilberforce Island, Bayelsa State 28
- Niger State College of Education, Minna, (Affl To Usmanu Danfodiyo Uni, Sokoto) 1
- Nigeria Maritime University, Okerenkoko, Delta State 1
- Nigerian Army University, Biu, Borno State 3
- Nile University of Nigeria, Abuja 3
- Nnamdi Azikiwe University, Awka, Anambra State 98
- Northwest University, Kano, Kano State 179