Effects of Hellenia Speciosa Leaf Extract on the Haematological Parameters of Stz Induced Diabetes in Albino Rats
Student: Immaculate EDOJAH OCHEJE (Project, 2025)
Department of Biochemistry
Cross Rivers University of Technology, Calabar, Cross Rivers State
Abstract
Diabetes mellitus is one of the most common endocrine disorders which causes microvascular and macrovascular complications. Herbal medicines derived from plant extracts are used to treat various diseases because of its fewer side effects. The present investigation focuses on determining the effects of Hellenia speciosa leaf extract on the haematological parameters of Stz induced diabetes in albino rats. The fresh Hellenia speciosa leaves were rinsed in clean water, then left to air dry at room temperature. Electric blender was used to blend the dried leaves, and a soxhlet extractor was used to extract the powdered leaves using ethanol. The oral administration of crude leaf extract in diabetic rats for 14 days at different dosage of 40 mg/kg body weight exhibited a significant reduction (p
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