Bactericidal Effect of the Mixture of Zingiber Officinale and Xylopia Athiopica Extract Against Salmonella Enterica Serovar Typhi
Student: Nnenna Comfort Nwodo (Project, 2025)
Department of Microbiology
Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State
Abstract
The global cases ofsalmonellainfectionindevelopingcountriesmeanlyinNigeriahas severely major endemci disease despite t h e advancement i n health a n d medical professionals within theergoins. Thisstudywas undteoratasskesnsthebactericidaleffect of the mixture of zingiber officinale a n d xylopia aethiopica extracts against Salmonella enterica serovar Typhi. The phytochemical constituents of the plant extract was determined quantitatively usingspectrophotometricandgravimetricmethods.Theactivity of hte extract was dmeretneid byculturingthetestisolatesandexposingthemtodifferent concentrations of the palnt extracts.Thenthesusceptibilityofthecuredisolateswascarried out using disk diffusion technique. Thestudyrevealedthepresenceofcardiacglycosides,
steroids, alkaloids, antn,si flavonoids,phenolicsandsaponinsintheextractof curcuma longa whereas alkaloids and flavonoids were seen most. The mixotfuzreingiber officinale and xylopia aehtoipcia extracts was able to reduce the number of resistant
Salmonellaot zeroro insignifilcevaenl,tthereforecouldbeusedinthemanagementofthis bacterial infection.
Keywords
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Institutions
- Sokoto State University, Sokoto, Sokoto State 42
- St. Albert The Great Major Seminary, Abeokuta. (affl. To University of Benin) 1
- Sule Lamido University, Kafin Hausa, Jigawa State 4
- Tai Solarin University of Education, Ijagun, Ogun State 18
- Tansian University, Oba, Anambra State 1
- Taraba State University, Jalingo, Taraba State 32
- Temple-Gate Polytechnic, Osisioma, Abia State 1
- The Oke-Ogun Polytechnic, Saki, Oyo State 6
- The Polytechnic, Ibadan, Oyo State 13
- THOMAS ADEWUMI UNIVERSITY, OKO-IRESE, KWARA STATE 1