Antidiabetic Activity and Qualitative Phytochemical Analysis of Aqueous Banana Blossom Extract
Student: Farida Salawu (Project, 2025)
Department of Pure and Applied Chemistry
Kaduna State University, Kaduna, Kaduna State
Abstract
Diabetes mellitus, a chronic condition characterized by elevated blood glucose levels, necessitates the exploration of novel therapeutic agents. This study aimed to investigate the phytochemical composition and antidiabetic efficacy of ethyl acetate banana blossom extract in experimentally induced diabetic rats. The rats were divided into three groups and received either normal saline, metformin, or extract via oral administration for 14 days. Blood glucose levels and body weight were monitored at regular intervals. The findings revealed that the extract significantly mitigated blood glucose levels and enhanced body weight in diabetic rats. Phytochemical analysis detected the presence of flavonoids, phenolic acids, and saponins, which may contribute to the extract's antidiabetic properties. Notably, the extract exhibited a more pronounced antidiabetic effect compared to metformin. While the exact mechanisms underlying this effect remain unclear, they may involve insulin secretion stimulation, insulin sensitivity improvement, and glucose absorption reduction.
Keywords
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- UMA UKPAI SCHOOL OF THEOLOGY, UYO, AKWA IBOM STATE (AFFL TO UNIVERSITY OF UYO) 1
- Umaru Ali Shinkafi Polytechnic, Sokoto, Sokoto State 24
- Umaru Musa Yaradua University, Katsina, Katsina State 28
- Umca, Ilorin (Affiliated To University of Ibadan), Kwara State 1
- University of Abuja, Abuja, Fct 116
- University of Africa, Toru-Orua, Bayelsa State 4
- University of Benin, Benin City, Edo State 362
- University of Calabar Teaching Hospital School of Health Information Mgt. 1
- University of Calabar, Calabar, Cross River State 239
- University of Ibadan, Ibadan, Oyo State 14