Comparative Analysis of Different Types of Hematoxylin on Cancerous Tissues

Student: Zimi Beauty Tuomokeme (Thesis, 2025)
Department of Medical Laboratory Science
Igbinedion University, Okada, Benin City, Edo State

Abstract

Hematoxylin remains the most widely used stain in histology, primarily for nuclear counterstaining despite advances in molecular methods. This study compares Cole’s, Ehrlich’s, Gill’s, and Harris’ hematoxylins on breast cancer tissues, using six blocks to produce 24 slides (six per stain). Results show Ehrlich’s and Cole’s yielding brilliant staining, ideal for histological analysis, while Gill’s was average and Harris’ poor, making the latter two unsuitable for breast cancer tissues.

Keywords

Hematoxylin His to pathology breast cancer staining techniques

For the full publication, please contact the author directly at: zimi.tuomokeme@iuokada.edu.ng

Filters

Institutions

Osun State College of Education, Ila-Orangun(Aff To Ekiti State Uni), Osun State 1
Osun State College of Education, Ilesa, Osun State. (affl To Univ of Ibadan) 2
Osun State Polytechnic, Iree, Osun State 468
Osun State University, Osogbo, Osun State 11
Our Saviour Institute of Science and Technology (polytechnic) Enugu, Enugu State 1
PAN-ATLANTIC UNIVERSITY, KM 52 LEKKI-EPE EXPRESSWAY, IBEJU-LEKKI, LAGOS STATE. 14
Paul University, Awka, Anambra State 2
Petroleum Training Institute, Effurun, Delta State 1
Precious Cornerstone University, Ibadan, Oyo State 1
Prince Abubakar Audu University, Anyigba 30