Comparative Analysis of Different Types of Hematoxylin on Cancerous Tissues

Student: Zimi Beauty Tuomokeme (Thesis, 2025)
Department of Medical Laboratory Science
Igbinedion University, Okada, Benin City, Edo State

Abstract

Hematoxylin remains the most widely used stain in histology, primarily for nuclear counterstaining despite advances in molecular methods. This study compares Cole’s, Ehrlich’s, Gill’s, and Harris’ hematoxylins on breast cancer tissues, using six blocks to produce 24 slides (six per stain). Results show Ehrlich’s and Cole’s yielding brilliant staining, ideal for histological analysis, while Gill’s was average and Harris’ poor, making the latter two unsuitable for breast cancer tissues.

Keywords

Hematoxylin His to pathology breast cancer staining techniques

For the full publication, please contact the author directly at: zimi.tuomokeme@iuokada.edu.ng

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Institutions

UMA UKPAI SCHOOL OF THEOLOGY, UYO, AKWA IBOM STATE (AFFL TO UNIVERSITY OF UYO) 1
Umaru Ali Shinkafi Polytechnic, Sokoto, Sokoto State 24
Umaru Musa Yaradua University, Katsina, Katsina State 28
Umca, Ilorin (Affiliated To University of Ibadan), Kwara State 1
University of Abuja, Abuja, Fct 117
University of Africa, Toru-Orua, Bayelsa State 4
University of Benin, Benin City, Edo State 362
University of Calabar Teaching Hospital School of Health Information Mgt. 1
University of Calabar, Calabar, Cross River State 240
University of Ibadan, Ibadan, Oyo State 14