Comparative Analysis of Different Types of Hematoxylin on Cancerous Tissues

Student: Zimi Beauty Tuomokeme (Thesis, 2025)
Department of Medical Laboratory Science
Igbinedion University, Okada, Benin City, Edo State

Abstract

Hematoxylin remains the most widely used stain in histology, primarily for nuclear counterstaining despite advances in molecular methods. This study compares Cole’s, Ehrlich’s, Gill’s, and Harris’ hematoxylins on breast cancer tissues, using six blocks to produce 24 slides (six per stain). Results show Ehrlich’s and Cole’s yielding brilliant staining, ideal for histological analysis, while Gill’s was average and Harris’ poor, making the latter two unsuitable for breast cancer tissues.

Keywords

Hematoxylin His to pathology breast cancer staining techniques

For the full publication, please contact the author directly at: zimi.tuomokeme@iuokada.edu.ng

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Institutions

Al-Hikmah University, Ilorin, Kwara State 2
AL-ISTIQAMAH UNIVERSITY, SUMAILA, KANO STATE 1
Al-Qalam University, Katsina, Katsina State 5
Alex Ekwueme Federal University, Ndufu-Alike, Ebonyi State 87
Alvan Ikoku College of Education, Imo State, (Affl To Univ of Nigera, Nsukka) 11
Ambrose Alli University, Ekpoma, Edo State 478
Anambra State College of Health Technology, Obosi, Anambra State 1
Auchi Polytechnic, Auchi, Edo State 503
Auchi Polytechnic, Auchi, Edo State. (affl To Nnamdi Azikiwe University, Awka) 3
Audu Bako College of Agriculture Danbatta, Kano, Kano State 54