Sub-Acute Effect of Administration of High Dose of Skushies on Lipid Profile in Wistar Rats
Student: Sylvia Chinonyelum Izediuno (Project, 2025)
Department of Human Physiology
Delta State University, Abraka, Delta State
Abstract
This research examines the impact of high doses of skushies on certain lipid profile parameters in Wistar rats and compares the results with findings from other relevant studies. Four groups of Wistar rats were used: a control group (Group 1), a low dose (17.5 mg/kg, Group 2), a medium dose (35 mg/kg, Group 3), and high dose (70 mg/kg, Group 4). The study specifically focused on the control group (Group 1) and the high dose (Group 4). Measurement of total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL), triglyceride (TG) and very low density lipoprotein(VLDL) were taken and compared using a one-way analysis of variance (ANOVA). Results indicated that high dose administration of skushies altered these parameters compared to the control group. Further research is needed to understand the mechanisms behind the significant decrease in TG, and significant increase in HDL and TC observed in the high dose. There was no significant difference in LDL and VLDL.
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For the full publication, please contact the author directly at: sylvialorraine572@gmail.com
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- Landmark University, Omu-Aran, Kwara State 1
- Lead City University, Ibadan, Oyo State 1
- Lens Polytechnic, offa, Kwara State. 215
- Madonna University, Elele, Rivers State 20
- Madonna University, Okija, Anambra State 2
- Mcpherson University, Seriki Sotayo, Ogun State 1
- Michael and Cecilia Ibru University, Owhrode, Delta State 1
- Michael Okpara University of Agriculture, Umudike 43
- Michael Otedola Col of Primary Educ. Epe, Lagos (affl To University of Ibadan) 8
- Modibbo Adama University, Yola, Adamawa State 15