In Vitro Antiplasmodial Activity of Antimalarial Herbal Mixture (agbo), Sold in Kano, Nigeria.
Student: Abubakar Abdullahi Garba (Project, 2025)
Department of Biochemistry
Bayero University, Kano, Kano State
Abstract
The aim of the project is to determine the in vitro Antiplasmodial activity of antimalarial herbal mixture (Agbo), sold in kano state, Nigeria. The 3 plant samples A, B and C were collected from three different locations in kano state and the extraction was carried out in ethanol. The filtered sterilized extracts (10, 5, 2.5, 1.25) mg/ml were tested for antiplamodial activity against Plasmodium parasites. The phytochemical constituents in the potential extracts were also detected. Result: Of the selected plant species or samples, sample the bark of Switenia macrophylla showed an excellent antiplasmodial activity, followed by sample B root of Anisopus manni, while sample C bark of Anageisus leiocarpus revealed significant antiplasmodial activity, between the concentration and time of incubation exposure. The in vitro antiplasmodial activity might be due to the presence of alkaloids, flavanoids, tannins, glycosides, saponins among others in the ethanolic extracts of the tested plant samples. the ethanolic extracts possess lead compounds for development of antiplasmodial drugs.
Keywords
For the full publication, please contact the author directly at: abubakarabdullahigarba781@gmail.com
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Institutions
- Isa Mustapha Agwai I Polytechnic, Lafia, Nasarawa State 2
- Jigawa State Polytechnic, Dutse, Jigawa State 4
- Joseph Sarwuan Tarka University, Makurdi, Benue State 17
- Kaduna Polytechnic (NCE), Kaduna, Kaduna State 2
- Kaduna Polytechnic, Kaduna 328
- Kaduna Polytechnic, Kaduna , Kaduna State (affl To Fed Univ of Tech, Minna) 6
- Kaduna State College of Education, Gidan-Waya (affliatted To Abu) 2
- Kaduna State University, Kaduna, Kaduna State 246
- Kano State Polytechnic, Kano, Kano State 196
- Kano University of Science and Technology, Wudil, Kano State 6