In Vitro Antiplasmodial Activity of Antimalarial Herbal Mixture (agbo), Sold in Kano, Nigeria.
Student: Abubakar Abdullahi Garba (Project, 2025)
Department of Biochemistry
Bayero University, Kano, Kano State
Abstract
The aim of the project is to determine the in vitro Antiplasmodial activity of antimalarial herbal mixture (Agbo), sold in kano state, Nigeria. The 3 plant samples A, B and C were collected from three different locations in kano state and the extraction was carried out in ethanol. The filtered sterilized extracts (10, 5, 2.5, 1.25) mg/ml were tested for antiplamodial activity against Plasmodium parasites. The phytochemical constituents in the potential extracts were also detected. Result: Of the selected plant species or samples, sample the bark of Switenia macrophylla showed an excellent antiplasmodial activity, followed by sample B root of Anisopus manni, while sample C bark of Anageisus leiocarpus revealed significant antiplasmodial activity, between the concentration and time of incubation exposure. The in vitro antiplasmodial activity might be due to the presence of alkaloids, flavanoids, tannins, glycosides, saponins among others in the ethanolic extracts of the tested plant samples. the ethanolic extracts possess lead compounds for development of antiplasmodial drugs.
Keywords
For the full publication, please contact the author directly at: abubakarabdullahigarba781@gmail.com
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Institutions
- AVE-MARIA UNIVERSITY, PIYANKO, NASARAWA STATE 1
- Babcock University, Ilishan-Remo, Ogun State 7
- Bamidele Olumilua University of Edu. Science and Tech. Ikere Ekiti, Ekiti State 454
- Bauchi State College of Agriculture, Bauchi, Bauchi State 1
- Bauchi State University, Gadau, Bauchi State 16
- Bayelsa State Polytechnic, Aleibiri, Bayelsa State 13
- Bayero University, Kano, Kano State 586
- Benue State Polytechnic, Ugbokolo, Benue State 10
- Benue State University, Makurdi, Benue State 47
- Bingham University, Karu, Nasarawa State 3