Effects of Bisphenol-a and Selenium on Luteinizing Hormone in Male Wistar Rats
Student: Eniye Peace Tiemo (Project, 2025)
Department of Physiology
University of Benin, Benin City, Edo State
Abstract
Bisphenol- A (BPA) acts as an endocrine-disrupting chemical (EDC) by interfering with the hypothalamic-pituitary-gonadal (HPG) axis. Selenium possess antioxidant and anti-inflammatory properties that help to regulate immune cell functions. Luteinizing hormone (LH) is a glycoprotein hormone that is co-secreted along with follicle-stimulating hormone by the gonadotrophin cells in the adenohypophysis. The aim of this study is to determine the effects of Bisphenol-A and selenium on luetinizing hormone (LH) in adult male wistar rats. A total of twenty (20) adult male Wistar rats weighing between 180g and 200g were purchased. After acclimatization period, the rats were allocated into 4 groups of five rats each designated as groups A, B, C, D.
Keywords
For the full publication, please contact the author directly at: eniye.tiemo@bmedsci.uniben.edu
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Institutions
- HASSAN USMAN KATSINA POLYTECHNIC (NCE), KATSINA, KATSINA STATE 4
- Hassan Usman Katsina Polytechnic, Katsina, Katsina State 5
- Heritage Polytechnic, Ikot Udota, Akwa Ibom State 46
- Hussaini Adamu Federal Polytechnic, Kazaure, Jigawa State 8
- Ibrahim Badamasi Babangida University, Lapai, Niger State 24
- Igbinedion University, Okada, Benin City, Edo State 2
- Ignatius Ajuru University of Education, Port Harcourt, Rivers State 8
- Imo State Polytechnic, Umuagwo, Owerri, Imo State 3
- Imo State University, Owerri, Imo State 45
- Institute of Management and Technology, Enugu, Enugu State 11