Effects of Bisphenol-a and Selenium on Luteinizing Hormone in Male Wistar Rats
Student: Eniye Peace Tiemo (Project, 2025)
Department of Physiology
University of Benin, Benin City, Edo State
Abstract
Bisphenol- A (BPA) acts as an endocrine-disrupting chemical (EDC) by interfering with the hypothalamic-pituitary-gonadal (HPG) axis. Selenium possess antioxidant and anti-inflammatory properties that help to regulate immune cell functions. Luteinizing hormone (LH) is a glycoprotein hormone that is co-secreted along with follicle-stimulating hormone by the gonadotrophin cells in the adenohypophysis. The aim of this study is to determine the effects of Bisphenol-A and selenium on luetinizing hormone (LH) in adult male wistar rats. A total of twenty (20) adult male Wistar rats weighing between 180g and 200g were purchased. After acclimatization period, the rats were allocated into 4 groups of five rats each designated as groups A, B, C, D.
Keywords
For the full publication, please contact the author directly at: eniye.tiemo@bmedsci.uniben.edu
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Institutions
- UMA UKPAI SCHOOL OF THEOLOGY, UYO, AKWA IBOM STATE (AFFL TO UNIVERSITY OF UYO) 1
- Umaru Ali Shinkafi Polytechnic, Sokoto, Sokoto State 24
- Umaru Musa Yaradua University, Katsina, Katsina State 28
- Umca, Ilorin (Affiliated To University of Ibadan), Kwara State 1
- University of Abuja, Abuja, Fct 117
- University of Africa, Toru-Orua, Bayelsa State 4
- University of Benin, Benin City, Edo State 362
- University of Calabar Teaching Hospital School of Health Information Mgt. 1
- University of Calabar, Calabar, Cross River State 240
- University of Ibadan, Ibadan, Oyo State 14