Effects of Bisphenol-a and Selenium on Luteinizing Hormone in Male Wistar Rats
Student: Eniye Peace Tiemo (Project, 2025)
Department of Physiology
University of Benin, Benin City, Edo State
Abstract
Bisphenol- A (BPA) acts as an endocrine-disrupting chemical (EDC) by interfering with the hypothalamic-pituitary-gonadal (HPG) axis. Selenium possess antioxidant and anti-inflammatory properties that help to regulate immune cell functions. Luteinizing hormone (LH) is a glycoprotein hormone that is co-secreted along with follicle-stimulating hormone by the gonadotrophin cells in the adenohypophysis. The aim of this study is to determine the effects of Bisphenol-A and selenium on luetinizing hormone (LH) in adult male wistar rats. A total of twenty (20) adult male Wistar rats weighing between 180g and 200g were purchased. After acclimatization period, the rats were allocated into 4 groups of five rats each designated as groups A, B, C, D.
Keywords
For the full publication, please contact the author directly at: eniye.tiemo@bmedsci.uniben.edu
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- Mohammed Lawan College of Agriculture, Maiduguri, Borno State 12
- Moshood Abiola Polytechnic, Abeokuta, Ogun State 7
- Nasarawa State University, Keffi, Nasarawa State 8
- Niger Delta University, Wilberforce Island, Bayelsa State 28
- Niger State College of Education, Minna, (Affl To Usmanu Danfodiyo Uni, Sokoto) 1
- Nigeria Maritime University, Okerenkoko, Delta State 1
- Nigerian Army University, Biu, Borno State 3
- Nile University of Nigeria, Abuja 3
- Nnamdi Azikiwe University, Awka, Anambra State 98
- Northwest University, Kano, Kano State 179