Effect of Aqueous Extarct of Phyllantus Amarus on Paracetamol Induced Liver Damage of Wister Albino Rats
Student: Eruchiokike Henry-Ihunda (Project, 2025)
Department of Biochemistry
University of Port-Harcourt, Rivers State
Abstract
The effect of aqueous extract of Phyllantus amarus on paracetamol induced liver damage in wister albino rats in-vitro was investigated. The liver function markers; Alanine transaminase (ALP), Aspartate transaminase (ALT), Alakaline phosphate (ALP), Albumin, Total protein, Total bilirubin and Glucose were measured and the results show that after the adminstration of paracetamol, the concentration of ALP, ALT, AST, Albumin, Total Protein, Total Bilirubin, Glucose in the serum increased as a result of the damaged liver but on administration of varying concentration of the extract over a period of seven days, there was a significant reduction in the concentrations. The result proves that the leaves of Phyllantus amarus have hepatoprotective effect on paracetamol induced liver damage
Keywords
For the full publication, please contact the author directly at: reaganhenry44@gmail.com
Filters
Institutions
- Mohammed Lawan College of Agriculture, Maiduguri, Borno State 12
- Moshood Abiola Polytechnic, Abeokuta, Ogun State 7
- Nasarawa State University, Keffi, Nasarawa State 8
- Niger Delta University, Wilberforce Island, Bayelsa State 28
- Niger State College of Education, Minna, (Affl To Usmanu Danfodiyo Uni, Sokoto) 1
- Nigeria Maritime University, Okerenkoko, Delta State 1
- Nigerian Army University, Biu, Borno State 3
- Nile University of Nigeria, Abuja 3
- Nnamdi Azikiwe University, Awka, Anambra State 98
- Northwest University, Kano, Kano State 179