Comparative Assessment of the Mitigating Effect of Edta and Selected Plant Exracts on Lead Toxicity of the Renal System
Student: Sandra Nwokoro (Project, 2025)
Department of Biotechnology
Alex Ekwueme Federal University, Ndufu-Alike, Ebonyi State
Abstract
ABSTRACT
Lead is a heavy metal found naturally and released by human activities, poses grave health risks, especially for children. It can harm multiple organs, including the kidneys. This study investigates the renal effects of lead and compares the potentials of selected plant extracts and EDTA to mitigate them using 42 albino rats. The normal control (A) group received feed and water only, while lead control (B) group received 50 mg/kg of lead. The treatment groups received lead and 15mg/kg of EDTA (group C), 300mg/g of ginger and garlic (spice) (Group D), turmeric (E), watermelon (F) and citrus (group G) respectively. The study administered treatments orally for 42 days after which the animals were fasted overnight (8 h) and sacrificed and collected blood into Heparin bottles for analysis. Results showed significant(P
Keywords
For the full publication, please contact the author directly at: eberesandra25@gmail.com
Filters
Institutions
- Landmark University, Omu-Aran, Kwara State 1
- Lead City University, Ibadan, Oyo State 1
- Lens Polytechnic, offa, Kwara State. 215
- Madonna University, Elele, Rivers State 20
- Madonna University, Okija, Anambra State 2
- Mcpherson University, Seriki Sotayo, Ogun State 1
- Michael and Cecilia Ibru University, Owhrode, Delta State 1
- Michael Okpara University of Agriculture, Umudike 43
- Michael Otedola Col of Primary Educ. Epe, Lagos (affl To University of Ibadan) 8
- Modibbo Adama University, Yola, Adamawa State 15