Effect of Aqueous Extract of Gongronema Latifolium Leaves on the Liver Function Parameters of Albino Rats
Student: Miracle Chibuchi John (Project, 2025)
Department of Pharmaceutical Technology
Federal Polytechnic, Nekede, Imo State
Abstract
ABSTRACT The effect of various concentration of aqueous extract of Gongronema Latifolium leaves on some liver function parameters; alanine and aspartate aminotransferase and alkaline phosphatase were investigated in albino Wister strain rats. The classes of chemical components of the aqueous extract of the plant were determined. Glycosides, alkaloids, carbohydrates, saponins,tannins, and flavonoids, were found to be present while cyanogenetic glycosides was not detected. The activities of aspartate aminotransferases increased for all concentration(p0.05)for all the concentrations administered. The results therefore, strongly suggest that Gongronema Latifolium leafextract may not have hepatotoxic effect when used as nutritional or therapeutic agent.
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- Federal Polytechnic, Mubi, Adamawa State 20
- Federal Polytechnic, Nasarawa, Nasarawa State 59
- Federal Polytechnic, Nekede, Imo State 53
- Federal Polytechnic, offa, Kwara State 18
- Federal Polytechnic, Oko, Anambra State 8
- Federal School of Biomedical Engineering, (LUTH), Idi-Araba, Lagos State 1
- Federal School of Surveying, Oyo, Oyo State 7
- Federal University of Agriculture, Abeokuta, Ogun State 19
- Federal University of Petroleum Resources, Effurun, Delta State 77
- Federal University of Technology Akure, Ondo State 23