Effect of Aqueous Extract of Gongronema Latifolium Leaves on the Liver Function Parameters of Albino Rats
Student: Miracle Chibuchi John (Project, 2025)
Department of Pharmaceutical Technology
Federal Polytechnic, Nekede, Imo State
Abstract
ABSTRACT The effect of various concentration of aqueous extract of Gongronema Latifolium leaves on some liver function parameters; alanine and aspartate aminotransferase and alkaline phosphatase were investigated in albino Wister strain rats. The classes of chemical components of the aqueous extract of the plant were determined. Glycosides, alkaloids, carbohydrates, saponins,tannins, and flavonoids, were found to be present while cyanogenetic glycosides was not detected. The activities of aspartate aminotransferases increased for all concentration(p0.05)for all the concentrations administered. The results therefore, strongly suggest that Gongronema Latifolium leafextract may not have hepatotoxic effect when used as nutritional or therapeutic agent.
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- Novena University, Ogume, Delta State 1
- Nuhu Bamalli Polytechnic, Zaria, Kaduna State 7
- Nwafor Orizu College of Education, Nsugbe, Anambra State 1
- Obafemi Awolowo University, Ile-Ife, Osun State 15
- Oduduwa University, Ipetumodu, Osun State 9
- Ogun State College of Health Technology, Ilese-Ijebu, Ogun State 1
- Ogun State Institute of Tech(formerly Gateway Ict Poly), Igbesa, Ogun State 4
- Olabisi Onabanjo University, Ago-Iwoye, Ogun State 38
- Ondo State University of Medical Sciences, Laje Road, Ondo, Ondo State 1
- Osun State College of Education, Ila-Orangun 1