Effect of Aqueous Extract of Gongronema Latifolium Leaves on the Liver Function Parameters of Albino Rats
Student: Miracle Chibuchi John (Project, 2025)
Department of Pharmaceutical Technology
Federal Polytechnic, Nekede, Imo State
Abstract
ABSTRACT The effect of various concentration of aqueous extract of Gongronema Latifolium leaves on some liver function parameters; alanine and aspartate aminotransferase and alkaline phosphatase were investigated in albino Wister strain rats. The classes of chemical components of the aqueous extract of the plant were determined. Glycosides, alkaloids, carbohydrates, saponins,tannins, and flavonoids, were found to be present while cyanogenetic glycosides was not detected. The activities of aspartate aminotransferases increased for all concentration(p0.05)for all the concentrations administered. The results therefore, strongly suggest that Gongronema Latifolium leafextract may not have hepatotoxic effect when used as nutritional or therapeutic agent.
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Institutions
- Ekiti State University 58
- Ekiti State University, Ado-Ekiti, Ekiti State 881
- Elizade University, Ilara-Mokin, Ondo State 100
- Emmanuel Alayande College of Education, Oyo. (affl To Ekiti State Univ) 2
- Enugu State Polytechnic, Iwollo, Enugu State 4
- Enugu State University of Science and Technology, Enugu, Enugu State 29
- Evangel University, Akaeze, Ebonyi State 2
- FCT COLLEGE OF EDUCATION, ZUBA ,( AFFILIATED TO ABU, ZARIA), FCT-ABUJA 5
- Federal College of Agricultural Produce Tech, Hotoro Gra Ext, Kano, Kano State 2
- Federal College of Educ. (Special), Oyo, Oyo State (Aff To Uni. Ibadan) 10