Effect of Aqueous Extract of Gongronema Latifolium Leaves on the Liver Function Parameters of Albino Rats

Student: Miracle Chibuchi John (Project, 2025)
Department of Pharmaceutical Technology
Federal Polytechnic, Nekede, Imo State

Abstract

ABSTRACT The effect of various concentration of aqueous extract of Gongronema Latifolium leaves on some liver function parameters; alanine and aspartate aminotransferase and alkaline phosphatase were investigated in albino Wister strain rats. The classes of chemical components of the aqueous extract of the plant were determined. Glycosides, alkaloids, carbohydrates, saponins,tannins, and flavonoids, were found to be present while cyanogenetic glycosides was not detected. The activities of aspartate aminotransferases increased for all concentration(p0.05)for all the concentrations administered. The results therefore, strongly suggest that Gongronema Latifolium leafextract may not have hepatotoxic effect when used as nutritional or therapeutic agent.

Keywords
effect aqueous extract gongronema latifolium leaves liver function parameters albino
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