Effect of Aqueous Extract of Gongronema Latifolium Leaves on the Liver Function Parameters of Albino Rats
Student: Miracle Chibuchi John (Project, 2025)
Department of Pharmaceutical Technology
Federal Polytechnic, Nekede, Imo State
Abstract
ABSTRACT The effect of various concentration of aqueous extract of Gongronema Latifolium leaves on some liver function parameters; alanine and aspartate aminotransferase and alkaline phosphatase were investigated in albino Wister strain rats. The classes of chemical components of the aqueous extract of the plant were determined. Glycosides, alkaloids, carbohydrates, saponins,tannins, and flavonoids, were found to be present while cyanogenetic glycosides was not detected. The activities of aspartate aminotransferases increased for all concentration(p0.05)for all the concentrations administered. The results therefore, strongly suggest that Gongronema Latifolium leafextract may not have hepatotoxic effect when used as nutritional or therapeutic agent.
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Institutions
- Adeseun Ogundoyin Polytechnic, Eruwa, Oyo State 1
- Adeyemi College of Education, Ondo State. (affl To Oau, Ile-Ife) 68
- Ahmadu Bello University, Zaria, Kaduna State 101
- Air Force Institute of Technology (Degree), Kaduna, Kaduna State 11
- Air Force Institute of Technology, Kaduna, Kaduna State 2
- Akanu Ibiam Federal Polytechnic, Unwana, Afikpo, Ebonyi State 6
- Akwa Ibom State University, Ikot-Akpaden, Akwa Ibom State 53
- Akwa Ibom State College of Edu, Afaha-Nsit (Affl To Uni Uyo), Akwa Ibom State 2
- AKWA-IBOM STATE POLYTECHNIC (IEI), IKOT-OSURUA, AKWA IBOM STATE 41
- Akwa-Ibom State Polytechnic, Ikot-Osurua, Akwa Ibom State 32