In Vitro Anticoagulant Effect of Ethanolic Leaf Extracts of Justicia Secunda (blood Root)
Student: Monsurat Ahuoyiza Abdulhameed (Project, 2025)
Department of Applied Biochemistry
Federal Polytechnic, Nasarawa, Nasarawa State
Abstract
This study evaluates the in vitro anticoagulant activity of ethanolic leaf extracts of Justicia secunda (commonly known as Blood root) using Prothrombin Time (PT) as a marker for coagulation inhibition. The plant extract yielded 53.4%, indicating a substantial presence of bioactive phytochemicals. Citrated human plasma was treated with varying extract concentrations (0.2 ml, 0.3 ml, and 0.5 ml) and compared to a positive control (3.2% sodium citrate; PT = 100.00 ± 0.73 sec) and a negative control (0.9% normal saline; PT = 12.00 ± 0.57 sec).
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For the full publication, please contact the author directly at: monsuratoyiza864@gmail.com
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- Kebbi State University of Science and Technology, Aliero, Kebbi State 6
- Kenule Benson Saro-Wiwa Polytechnic, Bori, Rivers State 18
- Kogi State Polytechnic, Lokoja, Kogi State 4
- Kogi State University, Anyigba 2
- Kwara State College of Health Technology, offa, Kwara State 9
- Kwara State Polytechnic, Ilorin, Kwara State 20
- Kwara State University, Malete, Ilorin, Kwara State 13
- Ladoke Akintola University of Technology, Ogbomoso, Oyo State 39
- Lagos State Poly, Ikorodu, Lagos State 2
- Lagos State University, Ojo, Lagos State 7