In Vitro Anticoagulant Effect of Ethanolic Leaf Extracts of Justicia Secunda (blood Root)
Student: Monsurat Ahuoyiza Abdulhameed (Project, 2025)
Department of Applied Biochemistry
Federal Polytechnic, Nasarawa, Nasarawa State
Abstract
This study evaluates the in vitro anticoagulant activity of ethanolic leaf extracts of Justicia secunda (commonly known as Blood root) using Prothrombin Time (PT) as a marker for coagulation inhibition. The plant extract yielded 53.4%, indicating a substantial presence of bioactive phytochemicals. Citrated human plasma was treated with varying extract concentrations (0.2 ml, 0.3 ml, and 0.5 ml) and compared to a positive control (3.2% sodium citrate; PT = 100.00 ± 0.73 sec) and a negative control (0.9% normal saline; PT = 12.00 ± 0.57 sec).
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For the full publication, please contact the author directly at: monsuratoyiza864@gmail.com
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Institutions
- Sokoto State University, Sokoto, Sokoto State 42
- St. Albert The Great Major Seminary, Abeokuta. (affl. To University of Benin) 1
- Sule Lamido University, Kafin Hausa, Jigawa State 4
- Tai Solarin University of Education, Ijagun, Ogun State 18
- Tansian University, Oba, Anambra State 1
- Taraba State University, Jalingo, Taraba State 32
- Temple-Gate Polytechnic, Osisioma, Abia State 1
- The Oke-Ogun Polytechnic, Saki, Oyo State 6
- The Polytechnic, Ibadan, Oyo State 13
- THOMAS ADEWUMI UNIVERSITY, OKO-IRESE, KWARA STATE 1