In Vitro Anticoagulant Effect of Ethanolic Leaf Extracts of Justicia Secunda (blood Root)
Student: Monsurat Ahuoyiza Abdulhameed (Project, 2025)
Department of Applied Biochemistry
Federal Polytechnic, Nasarawa, Nasarawa State
Abstract
This study evaluates the in vitro anticoagulant activity of ethanolic leaf extracts of Justicia secunda (commonly known as Blood root) using Prothrombin Time (PT) as a marker for coagulation inhibition. The plant extract yielded 53.4%, indicating a substantial presence of bioactive phytochemicals. Citrated human plasma was treated with varying extract concentrations (0.2 ml, 0.3 ml, and 0.5 ml) and compared to a positive control (3.2% sodium citrate; PT = 100.00 ± 0.73 sec) and a negative control (0.9% normal saline; PT = 12.00 ± 0.57 sec).
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For the full publication, please contact the author directly at: monsuratoyiza864@gmail.com
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Institutions
- Federal College of Education (Tech), Gusau, (Affl To Abu Zaria), Zamfara State 1
- Federal College of Education, Abeokuta (Aff To University of Ibadan), Ogun State 2
- Federal College of Education, Eha-Amufu, Enugu State 1
- Federal College of Education, Kano (Affl To Ahmadu Bello University, Zaria) 1
- Federal College of Education, Kontagora, (Affl To Abu, Zaria), Niger State 2
- Federal College of Education, Okene, (Affl. To University of Ibadan), Kogi State 3
- Federal College of Education, Pankshin, (Affl To Uni of Jos), Plateau State 2
- Federal College of Education, Zaria, Kaduna State (affl To Abu, Zaria) 1
- Federal College of Wildlife Management, New Bussa, Niger State 1
- Federal Cooperative College, Ibadan P.m.b. 5033, Eleyele, Ibadan, Oyo State 3