In Vitro Anticoagulant Effect of Ethanolic Leaf Extracts of Justicia Secunda (blood Root)
Student: Monsurat Ahuoyiza Abdulhameed (Project, 2025)
Department of Applied Biochemistry
Federal Polytechnic, Nasarawa, Nasarawa State
Abstract
This study evaluates the in vitro anticoagulant activity of ethanolic leaf extracts of Justicia secunda (commonly known as Blood root) using Prothrombin Time (PT) as a marker for coagulation inhibition. The plant extract yielded 53.4%, indicating a substantial presence of bioactive phytochemicals. Citrated human plasma was treated with varying extract concentrations (0.2 ml, 0.3 ml, and 0.5 ml) and compared to a positive control (3.2% sodium citrate; PT = 100.00 ± 0.73 sec) and a negative control (0.9% normal saline; PT = 12.00 ± 0.57 sec).
Keywords
For the full publication, please contact the author directly at: monsuratoyiza864@gmail.com
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- UMA UKPAI SCHOOL OF THEOLOGY, UYO, AKWA IBOM STATE (AFFL TO UNIVERSITY OF UYO) 1
- Umaru Ali Shinkafi Polytechnic, Sokoto, Sokoto State 24
- Umaru Musa Yaradua University, Katsina, Katsina State 28
- Umca, Ilorin (Affiliated To University of Ibadan), Kwara State 1
- University of Abuja, Abuja, Fct 116
- University of Africa, Toru-Orua, Bayelsa State 4
- University of Benin, Benin City, Edo State 362
- University of Calabar Teaching Hospital School of Health Information Mgt. 1
- University of Calabar, Calabar, Cross River State 239
- University of Ibadan, Ibadan, Oyo State 14