Effects of Immune Booster on Gastric Oxidative Marker in Lead Exposed Male Wistar Rats.
Student: Deborah Tomilolaninuoluwa Aigboviose (Project, 2025)
Department of Physiology
Ekiti State University, Ado-Ekiti, Ekiti State
Abstract
Lead exposure is a significant environmental risk factor that can induce oxidative stress and impair gastric health. This study investigated the effects of an immune booster on gastric oxidative markers in lead-exposed male Wistar rats. Thirty male Wistar rats were divided into five groups: control, lead-exposed, lead-exposed + immune booster (low dose), lead-exposed + immune booster (high dose), and immune booster alone. Lead exposure was achieved through administration of lead acetate (100 mg/kg) for 4 weeks, while the immune booster was administered concurrently. Gastric tissues were assessed for malondialdehyde (MDA), glutathione (GSH), and catalase (CAT) activities.
Results showed that lead exposure significantly increased MDA levels (p
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- Federal Polytechnic, Mubi, Adamawa State 20
- Federal Polytechnic, Nasarawa, Nasarawa State 59
- Federal Polytechnic, Nekede, Imo State 52
- Federal Polytechnic, offa, Kwara State 18
- Federal Polytechnic, Oko, Anambra State 8
- Federal School of Biomedical Engineering, (LUTH), Idi-Araba, Lagos State 1
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- Federal University of Agriculture, Abeokuta, Ogun State 19
- Federal University of Petroleum Resources, Effurun, Delta State 77
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