Effects of Immune Booster on Gastric Oxidative Marker in Lead Exposed Male Wistar Rats.
Student: Deborah Tomilolaninuoluwa Aigboviose (Project, 2025)
Department of Physiology
Ekiti State University, Ado-Ekiti, Ekiti State
Abstract
Lead exposure is a significant environmental risk factor that can induce oxidative stress and impair gastric health. This study investigated the effects of an immune booster on gastric oxidative markers in lead-exposed male Wistar rats. Thirty male Wistar rats were divided into five groups: control, lead-exposed, lead-exposed + immune booster (low dose), lead-exposed + immune booster (high dose), and immune booster alone. Lead exposure was achieved through administration of lead acetate (100 mg/kg) for 4 weeks, while the immune booster was administered concurrently. Gastric tissues were assessed for malondialdehyde (MDA), glutathione (GSH), and catalase (CAT) activities.
Results showed that lead exposure significantly increased MDA levels (p
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- Landmark University, Omu-Aran, Kwara State 1
- Lead City University, Ibadan, Oyo State 1
- Lens Polytechnic, offa, Kwara State. 215
- Madonna University, Elele, Rivers State 20
- Madonna University, Okija, Anambra State 2
- Mcpherson University, Seriki Sotayo, Ogun State 1
- Michael and Cecilia Ibru University, Owhrode, Delta State 1
- Michael Okpara University of Agriculture, Umudike 43
- Michael Otedola Col of Primary Educ. Epe, Lagos (affl To University of Ibadan) 8
- Modibbo Adama University, Yola, Adamawa State 15