Effects of Uvaria Chamae Root Aqueous Extract on Uterine Function in Female Wistar Rats
Student: Stella Oluwapelumi Temitope (Project, 2025)
Department of Biochemistry
University of Ilorin, Kwara State
Abstract
This study was aimed to investigate the effects of aqueous root extract of Uvaria chamae, a medicinal plant widely used in African ethnomedicine, on uterine histology and reproductive function in female Wistar rats. Twenty eight healthy female rats average weight 123±33.5g were randomized into four groups (A–D)with 7 rats in each group. Group A served as the control and received distilled water, while Groups B, C, and D received 100,200 and 400 mg/kg of the extract orally for 28 days, respectively. At the end of the treatment, uterine tissues were harvested for biochemical, hormonal(FSH, LH,and Prolactin) and histological analysis.Results showed no statistically significant changes (p < 0.05) in uterine glycogen and progesterone levels across all groups. However, luteinizing hormone (LH) levels significantly increased in the treated groups (p
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For the full publication, please contact the author directly at: temitopestella02@gmail.com
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Institutions
- Redeemers University, Ede, Osun State 4
- Rhema University, Aba, Abia State 11
- Rivers State University of Science and Technology, Port Harcourt, Rivers State 3
- RIVERS STATE UNIVERSITY, PORT HARCOURT, RIVERS STATE 13
- Rufus Giwa Polytechnic, Owo, Ondo State 2
- Saadatu Rimi College of Edu, Kumbotso, Kano State (affiliated To Abu, Zaria) 1
- Salem University, Lokoja, Kogi State 4
- School of Health Information Mgt (Uch, Ibadan), Oyo State 5
- School of Health Information Mgt, Oau Teaching Hospital, Ile-Ife, Osun State 30
- Skyline University Nigeria, Kano, Kano State 2