Effects of Uvaria Chamae Root Aqueous Extract on Uterine Function in Female Wistar Rats
Student: Stella Oluwapelumi Temitope (Project, 2025)
Department of Biochemistry
University of Ilorin, Kwara State
Abstract
This study was aimed to investigate the effects of aqueous root extract of Uvaria chamae, a medicinal plant widely used in African ethnomedicine, on uterine histology and reproductive function in female Wistar rats. Twenty eight healthy female rats average weight 123±33.5g were randomized into four groups (A–D)with 7 rats in each group. Group A served as the control and received distilled water, while Groups B, C, and D received 100,200 and 400 mg/kg of the extract orally for 28 days, respectively. At the end of the treatment, uterine tissues were harvested for biochemical, hormonal(FSH, LH,and Prolactin) and histological analysis.Results showed no statistically significant changes (p < 0.05) in uterine glycogen and progesterone levels across all groups. However, luteinizing hormone (LH) levels significantly increased in the treated groups (p
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For the full publication, please contact the author directly at: temitopestella02@gmail.com
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Institutions
- Landmark University, Omu-Aran, Kwara State 1
- Lead City University, Ibadan, Oyo State 1
- Lens Polytechnic, offa, Kwara State. 215
- Madonna University, Elele, Rivers State 20
- Madonna University, Okija, Anambra State 2
- Mcpherson University, Seriki Sotayo, Ogun State 1
- Michael and Cecilia Ibru University, Owhrode, Delta State 1
- Michael Okpara University of Agriculture, Umudike 43
- Michael Otedola Col of Primary Educ. Epe, Lagos (affl To University of Ibadan) 8
- Modibbo Adama University, Yola, Adamawa State 15