Effects of Uvaria Chamae Root Aqueous Extract on Uterine Function in Female Wistar Rats
Student: Stella Oluwapelumi Temitope (Project, 2025)
Department of Biochemistry
University of Ilorin, Kwara State
Abstract
This study was aimed to investigate the effects of aqueous root extract of Uvaria chamae, a medicinal plant widely used in African ethnomedicine, on uterine histology and reproductive function in female Wistar rats. Twenty eight healthy female rats average weight 123±33.5g were randomized into four groups (A–D)with 7 rats in each group. Group A served as the control and received distilled water, while Groups B, C, and D received 100,200 and 400 mg/kg of the extract orally for 28 days, respectively. At the end of the treatment, uterine tissues were harvested for biochemical, hormonal(FSH, LH,and Prolactin) and histological analysis.Results showed no statistically significant changes (p < 0.05) in uterine glycogen and progesterone levels across all groups. However, luteinizing hormone (LH) levels significantly increased in the treated groups (p
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For the full publication, please contact the author directly at: temitopestella02@gmail.com
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Institutions
- Sokoto State University, Sokoto, Sokoto State 42
- St. Albert The Great Major Seminary, Abeokuta. (affl. To University of Benin) 1
- Sule Lamido University, Kafin Hausa, Jigawa State 4
- Tai Solarin University of Education, Ijagun, Ogun State 18
- Tansian University, Oba, Anambra State 1
- Taraba State University, Jalingo, Taraba State 32
- Temple-Gate Polytechnic, Osisioma, Abia State 1
- The Oke-Ogun Polytechnic, Saki, Oyo State 6
- The Polytechnic, Ibadan, Oyo State 13
- THOMAS ADEWUMI UNIVERSITY, OKO-IRESE, KWARA STATE 1