Effects of Uvaria Chamae Root Aqueous Extract on Uterine Function in Female Wistar Rats
Student: Stella Oluwapelumi Temitope (Project, 2025)
Department of Biochemistry
University of Ilorin, Kwara State
Abstract
This study was aimed to investigate the effects of aqueous root extract of Uvaria chamae, a medicinal plant widely used in African ethnomedicine, on uterine histology and reproductive function in female Wistar rats. Twenty eight healthy female rats average weight 123±33.5g were randomized into four groups (A–D)with 7 rats in each group. Group A served as the control and received distilled water, while Groups B, C, and D received 100,200 and 400 mg/kg of the extract orally for 28 days, respectively. At the end of the treatment, uterine tissues were harvested for biochemical, hormonal(FSH, LH,and Prolactin) and histological analysis.Results showed no statistically significant changes (p < 0.05) in uterine glycogen and progesterone levels across all groups. However, luteinizing hormone (LH) levels significantly increased in the treated groups (p
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For the full publication, please contact the author directly at: temitopestella02@gmail.com
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Institutions
- Covenant Polytechnic, Aba, Abia State 1
- Covenant University, Canaan Land, Ota, Ogun State 4
- Crawford University of Apostolic Faith Mission Faith City, Igbesa, Ogun State 2
- Crescent University, Abeokuta, Ogun State 1
- Cross Rivers University of Technology, Calabar, Cross Rivers State 142
- Delta State Polytechnic, Ogwashi-Uku, Delta State 11
- Delta State Polytechnic, Otefe, Delta State 13
- Delta State University, Abraka, Delta State 139
- Ebonyi State University, Abakaliki, Ebonyi State 17
- Edo University, Iyamho, Edo State 10