Synergistic Effects of Intermittent Fasting and Vitamin C on Liver Histology, Body Weight, and Fasting Blood Glucose in Glucose-Loaded Male Wistar Rats
Student: Ahmed Opeyemi Saheed (Project, 2025)
Department of Human Physiology
University of Ilorin, Kwara State
Abstract
The study evaluated the combined effects of intermittent fasting (IF) and Vitamin C on liver histology, body weight, and fasting blood glucose (FBG) in glucose-loaded male Wistar rats. While initial FBG levels were similar across groups, significant differences emerged by Week 3 and Week 5. Histological analysis revealed severe liver damage in the glucose-only group, moderate improvement with IF alone, and near-normal liver structure in the IF + Vitamin C group. These findings suggest a strong synergistic effect in reversing glucose-induced liver injury and restoring metabolic balance.
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For the full publication, please contact the author directly at: saheedahmedopeyemi5501@gmail.com
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- Federal University, Lokoja, Kogi State 1
- Federal University, Otuoke, Bayelsa State 20
- Federal University, Wukari, Taraba State 5
- Fidei Polytechnic, Gboko, Benue State 1
- First Technical University, Ibadan, Oyo State 2
- Fountain University, Osogbo, Osun State 20
- Gateway Ict Polytechnic, Saapade, Ogun State 9
- Godfrey Okoye University, Urgwuomu- Nike, Enugu State 4
- Gombe State University, Tudun Wada, Gombe, Gombe State 18
- Hallmark University, Ijebu-Itele,ogun State 1