Synergistic Effects of Intermittent Fasting and Vitamin C on Liver Histology, Body Weight, and Fasting Blood Glucose in Glucose-Loaded Male Wistar Rats
Student: Ahmed Opeyemi Saheed (Project, 2025)
Department of Human Physiology
University of Ilorin, Kwara State
Abstract
The study evaluated the combined effects of intermittent fasting (IF) and Vitamin C on liver histology, body weight, and fasting blood glucose (FBG) in glucose-loaded male Wistar rats. While initial FBG levels were similar across groups, significant differences emerged by Week 3 and Week 5. Histological analysis revealed severe liver damage in the glucose-only group, moderate improvement with IF alone, and near-normal liver structure in the IF + Vitamin C group. These findings suggest a strong synergistic effect in reversing glucose-induced liver injury and restoring metabolic balance.
Keywords
For the full publication, please contact the author directly at: saheedahmedopeyemi5501@gmail.com
Filters
Institutions
- Novena University, Ogume, Delta State 1
- Nuhu Bamalli Polytechnic, Zaria, Kaduna State 7
- Nwafor Orizu College of Education, Nsugbe, Anambra State 1
- Obafemi Awolowo University, Ile-Ife, Osun State 15
- Oduduwa University, Ipetumodu, Osun State 9
- Ogun State College of Health Technology, Ilese-Ijebu, Ogun State 1
- Ogun State Institute of Tech(formerly Gateway Ict Poly), Igbesa, Ogun State 4
- Olabisi Onabanjo University, Ago-Iwoye, Ogun State 38
- Ondo State University of Medical Sciences, Laje Road, Ondo, Ondo State 1
- Osun State College of Education, Ila-Orangun 1