Synergistic Effects of Intermittent Fasting and Vitamin C on Liver Histology, Body Weight, and Fasting Blood Glucose in Glucose-Loaded Male Wistar Rats
Student: Ahmed Opeyemi Saheed (Project, 2025)
Department of Human Physiology
University of Ilorin, Kwara State
Abstract
The study evaluated the combined effects of intermittent fasting (IF) and Vitamin C on liver histology, body weight, and fasting blood glucose (FBG) in glucose-loaded male Wistar rats. While initial FBG levels were similar across groups, significant differences emerged by Week 3 and Week 5. Histological analysis revealed severe liver damage in the glucose-only group, moderate improvement with IF alone, and near-normal liver structure in the IF + Vitamin C group. These findings suggest a strong synergistic effect in reversing glucose-induced liver injury and restoring metabolic balance.
Keywords
For the full publication, please contact the author directly at: saheedahmedopeyemi5501@gmail.com
Filters
Institutions
- Redeemers University, Ede, Osun State 4
- Rhema University, Aba, Abia State 11
- Rivers State University of Science and Technology, Port Harcourt, Rivers State 3
- RIVERS STATE UNIVERSITY, PORT HARCOURT, RIVERS STATE 13
- Rufus Giwa Polytechnic, Owo, Ondo State 2
- Saadatu Rimi College of Edu, Kumbotso, Kano State (affiliated To Abu, Zaria) 1
- Salem University, Lokoja, Kogi State 4
- School of Health Information Mgt (Uch, Ibadan), Oyo State 5
- School of Health Information Mgt, Oau Teaching Hospital, Ile-Ife, Osun State 30
- Skyline University Nigeria, Kano, Kano State 2